Diet, insulin and glucose tolerance in non-diabetic men in The Netherlands

In 1990 a cross-sectional survey was carried out on diet in relation to insulin in the Zutphen Elderly Study. The individual association of dietary fiber intake was inversely associated with the area under  the insulin curve. In 1970 the Zutphen Study also carried out a cross-sectional analysis on individual diet and glucose tolerance. The intake of saturated fatty acids and dietary cholesterol was positively related to fasting blood glucose. Pectin intake was inversely related to the area under the glucose curve. In 1989/1990 a 2-hour post-load oral glucose tolerance test was performed in the Dutch and Finnish cohorts, along with information on the habitual diet. An increase in consumption of vegetables, legumes, potatoes and fish during the 20-year follow-up was inversely related to the 2-hour glucose level.

Insulin levels (mean and standard deviation) during an oral glucose tolerance test in 389 men aged 70-89 years, by quartiles of dietary fiber intake: The Zutphen Elderly Study, 1990.

Insulin levels (mean and standard deviation) during an oral glucose tolerance test in 389 men aged 70-89 years, by quartiles of dietary fiber intake: The Zutphen Elderly Study, 1990.

Interpretation

Dietary fiber intake of individuals was inversely related to insulin levels in the cross-sectional surveys. Saturated fatty acids and dietary cholesterol were positively and pectin was inversely related to oral glucose tolerance levels in these cross-sectional surveys. An increase over time in the consumption of vegetables, legumes, potatoes and fish was inversely related to subsequent glucose tolerance.

About the Zutphen Elderly Study

The Zutphen Elderly Study is an extension of the original Zutphen Study with a sample of the same age where detailed information on the diet of all the participants was collected four times between 1985 and 2000.  Read more about the Zutphen (Elderly) Study.

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